Treatment of pretibial myxedema with intralesional immunomodulating therapy
نویسندگان
چکیده
منابع مشابه
Treatment of pretibial myxedema with intralesional immunomodulating therapy
OBJECTIVE Local immune regulation therapy has been one of the therapeutic methods used for the treatment of autoimmune thyroid disease in patients with pretibial myxedema (PTM). However, the poor response rate and high recurrence rate are still major problems. Whether a premixed corticosteroid, compound betamethasone, could enhance remission rate and decrease recurrence rate in patients with PT...
متن کاملIntralesional Hyaluronidase with Triamcinolone for Recalcitrant Pretibial Myxedema
INTRALESIONAL HYALURONIDASE WITH TRIAMCINOLONE FOR RECALCITRANT PRETIBIAL MYXEDEMA Abstract Pretibial myxedema resulting in progressively worsening cutaneous induration and expanding nodules can lead to pain, discomfort and functional impairment. Treatment of resistant lesions presents a special challenge whereby topical therapies are insufficient, and systemic therapies are met with poor toler...
متن کاملPre-tibial myxedema: treatment with intralesional corticosteroid*
The pretibial myxedema is a manifestation of Graves' disease characterized by accumulation of glycosaminoglycans in the reticular dermis. The dermopathy is self-limiting but in some cases may cause cosmetic and functional damage. Conventional treatment is use of topical steroids under occlusive dressing, however the intralesional application has shown good results. We present a case of pretibia...
متن کاملSevere pretibial myxedema.
Although pretibial myxedema (PTM) occurs in 4.3% of patients with Graves's disease, the most severe variant, elephantiasis nostras verrucosa, is found in less than 1% of cases. The most frequent location of infiltration is the lower extremities, especially the pretibial areas and on the dorsum of the foot. The authors report one of the most severe cases of elephantiasis nostras verrucosa, follo...
متن کاملA Randomized Controlled Trial of Intralesional Glucocorticoid for Treating Pretibial Myxedema
BACKGROUND Pretibial myxedema (PTM) is an uncommon dermopathy associated with autoimmune thyroid diseases. Now it is thought to be autoimmune and its treatment with glucocorticoid is helpful. However, it has not been evaluated. METHODS A prospective randomized controlled trial was performed in 110 patients with PTM to evaluate the efficacy and safety of triamcinolone acetonide with intralesio...
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ژورنال
عنوان ژورنال: Therapeutics and Clinical Risk Management
سال: 2017
ISSN: 1178-203X
DOI: 10.2147/tcrm.s143711